An Overview of Swine Flu
Posted by admin | Posted in infection | Posted on 24-07-2009
Swine flu or influenza is a condition caused by strains of subtypes of
Influenza A virus called H1N1, H1N2, H3N1, H3N2, and H3N3. These viruses
are common in pigs located in midwestern United States, Canada, South
America, Mexico, Mainland China, Japan, Taiwan, Europe, and other Eastern
Asian countries.
Transmission of influenza virus from swine to humans is relatively uncommon
and does not always result to human influenza but often leads to production
of antibodies in the blood. When properly cooked, pig meat does not have
the potential of passing the virus. Transmission that leads to human
influenza is called zoonotic swine flu.
People who work with pigs, particularly those with direct exposure, are at
greater risk of being infected with swine flu. Towards the middle of the
20th century, identification of influenza subtypes became likely paving the
way for an accurate diagnosis of transmission to humans. Since then, 50
infections have been confirmed and recorded.
It is rare for these strains of swine flu to be transmitted from one human
to another. In humans, the symptoms of swine flu are similar to common
influenza as well as influenza-like illness such as chills, sore throat,
fever, coughing, muscular pains, severe headache, and general discomfort.
The 2009 swine flu outbreak in humans was caused by a new strain of
influenza A virus subtype H1N1 which have genes that closely resemble swine
influenza. The root of this new strain is not known. According to the World
Health Organization for Animal Health, this new strain has not been
isolated in pigs. It is capable of human-to-human transmission and
manifests the normal symptoms of influenza.
Swine can be infected with human influenza such as the case of the 1918 flu
pandemic and the 2009 flu outbreak. Swine flu was first proposed as a
disease associated with humans during the 1918 flu pandemic. During that
time, pigs became simultaneously sick with humans.
Influenza virus as a cause of disease in pigs was first identified in 1930.
For the next six decades, strains of swine influenza became almost
exclusively H1N1. From 1997 to 2002, new strains of three varied subtypes
and 5 different genotypes were identified as the cause of influenza among
pigs in North America.
From 1997-1998, H3N2 strains developed. They included genes acquired
through reassortment of human, avian, and swine viruses and have been a
principal cause of wine influenza in North America. Reassortment between
H1N1 and H3N2 resulted to the development of H1N2. In Canada, a strain of
H4N6 resulted from the reassortment of avian and swine flu but was isolated
on a single farm.
The H1N1 variant of swine flu is one of the descendants of the strain that
brought about the 1918 flu pandemic. While persisting in pigs, the
descendants of the 1918 virus have also been transmitted throughout the
20th century which resulted to the usual seasonal influenza outbreaks.
It is interesting to note that direct infection from pigs to humans is
rare, with only 12 confirmed cases in the United States since 2005.
However, since the influenza strains remain in the pigs after they have
disappeared in the human population can make these pigs a reservoir where
the influenza virus could survive and later on transmitted to humans as
soon as their immunity to the strain is no longe effective.
Swine flu has been recorded as zoonosis in humans several times, oftentimes
with limited distribution and rarely with massive distribution. Swine
outbreaks are common and can lead to significant economic losses in the
industry, mainly leading to stunting and expanded market time. Swine
influneza, for instance, the British meat industry has experienced £65
million of losses annually.

